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2 Feb 2023
BMRC
Institute of Molecular and Cell Biology
G9a/GLP inhibition during ex vivo lymphocyte expansion increases in vivo cytotoxicity of engineered T cells against hepatocellular carcinoma
Maxine S. Y. Lam,
Jose Antonio Reales-Calderon,
Jin Rong Ow,
Joey J. Y. Aw,
Damien Tan,
Ragavi Vijayakumar,
Erica Ceccarello,
Tommaso Tabaglio,
Yan Ting Lim,
Wang Loo Chien,
Fritz Lai,
Anthony Tan Tanoto,
Qingfeng Chen,
Radoslaw M. Sobota,
Giulia Adriani,
Antonio Bertoletti,
Ernesto Guccione,
Andrea Pavesi
Nature Communications
25 Mar 2021
BMRC
Institute of Molecular and Cell Biology
Splice-Switching Antisense Oligonucleotides as a Targeted Intrinsic Engineering Tool for Generating Armored Redirected T Cells
Erica Ceccarello,
Tommaso Tabaglio,
Sarene Koh,
Vincent Oei,
Winnie Teo,
Owen Julianto Jonathan,
Andrea Pavesi,
Qingfeng Chen,
Antonio Bertoletti,
Keng Boon Wee,
Ernesto Guccione
Nucleic Acid Therapeutics
6 Dec 2019
BMRC
Singapore Immunology Network
Liver fibrosis and CD206+ macrophage accumulation are suppressed by anti-GM-CSF therapy
Alfonso Tan-Garcia,
Fritz Lai,
Joe Poh Sheng Yeong,
Sergio E. Irac,
Pei Y. Ng,
Rasha Msallam,
Jeffrey Chun Tatt Lim,
Lu-En Wai,
Christine Y. L. Tham,
Su P. Choo,
Tony Lim,
Dan Y. Young,
Roberta D’Ambrosio,
Elisabetta Degasperi,
Riccardo Perbellini,
Evan Newell,
Nina Le Bert,
Florent Ginhoux,
Antonio Bertoletti,
Qingfeng Chen,
Charles-Antoine Dutertre
JHEP Reports
1 Nov 2018
BMRC
Institute of Molecular and Cell Biology
Molecular Recalibration of PD-1+ Antigen-Specific T Cells from Blood and Liver
Itziar Otano,
David Escors,
Anna Schurich,
Harsimran Singh,
Francis Robertson,
Brian R. Davidson,
Giuseppe Fusai,
Frederick A. Vargas,
Zhi M.D. Tan,
Jia Y.J. Aw,
Navjyot Hansi,
Patrick T.F. Kennedy,
Shao-An Xue,
Hans J. Stauss,
Antonio Bertoletti,
Andrea Pavesi,
Mala K. Maini
Molecular Therapy
14 Jun 2017
BMRC
Institute of Molecular and Cell Biology
A 3D microfluidic model for preclinical evaluation of TCR-engineered T cells against solid tumors
Andrea Pavesi,
Anthony T. Tan,
Sarene Koh,
Adeline Chia,
Marta Colombo,
Emanuele Antonecchia,
Carlo Miccolis,
Erica Ceccarello,
Giulia Adriani,
Manuela T. Raimondi,
Roger D. Kamm,
Antonio Bertoletti
JCI Insight
25 Mar 2015
BMRC
Institute of Molecular and Cell Biology
Trained immunity in newborn infants of HBV-infected mothers
Michelle Hong,
Elena Sandalova,
Diana Low,
Adam J. Gehring,
Stefania Fieni,
Barbara Amadei,
Simonetta Urbani,
Yap-Seng Chong,
Ernesto Guccione,
Antonio Bertoletti
Nature Communications
26 Jun 2014
BMRC
Singapore Institute for Clinical Sciences
Toll-Like Receptor 8 Agonist and Bacteria Trigger Potent Activation of Innate Immune Cells in Human Liver
Juandy Jo,
Anthony T. Tan,
James E. Ussher,
Elena Sandalova,
Xin-Zi Tang,
Alfonso Tan-Garcia,
Natalie To,
Michelle Hong,
Adeline Chia,
Upkar S. Gill,
Patrick T. Kennedy,
Kai Chah Tan,
Kang Hoe Lee,
Gennaro De Libero,
Adam J. Gehring,
Christian B. Willberg,
Paul Klenerman,
Antonio Bertoletti,
Christopher M. Walker
PLoS Pathogens
1 Aug 2013
BMRC
Singapore Institute for Clinical Sciences
Mobilizing monocytes to cross-present circulating viral antigen in chronic infection
Adeline Chia,
Seng Gee Lim,
Carlo Ferrari,
Florent Ginhoux,
Antonio Bertoletti,
Muzlifah Haniffa,
Patrick T. Kennedy,
Zi Zong Ho,
Carolina Boni,
Amanda Shin,
Adam J. Gehring,
Nasirah Banu
Journal of Clinical Investigation
27 Jul 2012
BMRC
Singapore Immunology Network
Human Tissues Contain CD141hi Cross-Presenting Dendritic Cells with Functional Homology to Mouse CD103+ Nonlymphoid Dendritic Cells
Muzlifah Haniffa,
Amanda Shin,
Venetia Bigley,
Naomi McGovern,
Pearline Teo,
Peter See,
Pavandip Singh Wasan,
Xiao-Nong Wang,
Frano Malinarich,
Benoit Malleret,
Anis Larbi,
Pearlie Tan,
Helen Zhao,
Michael Poidinger,
Sarah Pagan,
Sharon Cookson,
Rachel Dickinson,
Ian Dimmick,
Ruth F. Jarrett,
Laurent Renia,
John Tam,
Colin Song,
John Connolly,
Jerry K.Y. Chan,
Adam Gehring,
Antonio Bertoletti,
Matthew Collin,
Florent Ginhoux
Immunity
19 Aug 2010
BMRC
Singapore Institute for Clinical Sciences
Contribution of Herpesvirus Specific CD8 T Cells to Anti-Viral T Cell Response in Humans
Elena Sandalova,
Diletta Laccabue,
Carolina Boni,
Anthony T. Tan,
Katja Fink,
Eng Eong Ooi,
Robert Chua,
Bahar Shafaeddin Schreve,
Carlo Ferrari,
Antonio Bertoletti,
Liisa Selin
PLoS Pathogens
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