Evaluation of the ZnO Nanopillar Surface for Disinfection Applications

Evaluation of the ZnO Nanopillar Surface for Disinfection Applications

ACS Applied Bio Materials

10.1021/acsabm.1c00767

http://dx.doi.org/10.1021/acsabm.1c00767

Siti Nurhanna Riduan, Guangshun Yi, Shujun Gao, Jeremy Pang Kern Tan, Yee Lin Tan, Yuan Yuan, Hongfang Lu, Shuyun Chng, Jin Ting Ong, Pei Yun Hon, Mohammad Yazid Abdad, Shawn Vasoo, Brenda SP Ang, Yi Yan Yang, Jackie Y. Ying, Yugen Zhang

Biochemistry (medical), Biomedical engineering, General Chemistry, Biomaterials

06 October 2021

Riduan, S. N., Yi, G., Gao, S., Tan, J. P. K., Tan, Y. L., Yuan, Y., Lu, H., Chng, S., Ong, J. T., Hon, P. Y., Abdad, M. Y., Vasoo, S., Ang, B. S., Yang, Y. Y., Ying, J. Y., & Zhang, Y. (2021). Evaluation of the ZnO Nanopillar Surface for Disinfection Applications. ACS Applied Bio Materials, 4(10), 7524–7531. https://doi.org/10.1021/acsabm.1c00767

Much attention has been devoted to the synthesis and antimicrobial studies of nanopatterned surfaces. However, factors contributing to their potential and eventual application, such as large-scale synthesis, material durability, and biocompatibility, are often neglected in such studies. In this paper, the ZnO nanopillar surface is found to be amenable to synthesis in large forms and stable upon exposure to highly accelerated lifetime tests (HALT) without any detrimental effect on its antimicrobial activity. Additionally, the material is effective against clinically isolated pathogens and biocompatible in vivo. These findings illustrate the broad applicability of ZnO nanopillar surfaces in the common equipment used in health-care and consumer industries.

Publisher Copyright

This research / project is supported by the National Research Foundation (NRF) - NRF Competitive Research Program
Grant Reference no. : NRF-CRP19-2017-02

This research is supported by core funding from: A*STAR, IBB
Grant Reference no. :

This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Applied Bio Materials, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acsabm.1c00767

https://oar.a-star.edu.sg/communities-collections/articles/18270

2576-6422

Institute of Bioengineering and Bioimaging