Surface Antimicrobial Treatment by Biocompatible, Vertically Aligned Layered Double Hydroxide Array

Surface Antimicrobial Treatment by Biocompatible, Vertically Aligned Layered Double Hydroxide Array

Advanced Materials Interfaces

10.1002/admi.202101872

http://dx.doi.org/10.1002/admi.202101872

Guangshun Yi, Shujun Gao, Hongfang Lu, Wei Zhi Khoo, Shaoqiong Liu, Shuyun Chng, Yi Yan Yang, Jackie Y. Ying, Yugen Zhang

Mechanical Engineering, Mechanics of Materials

07 February 2022

Yi, G., Gao, S., Lu, H., Khoo, W. Z., Liu, S., Chng, S., Yang, Y. Y., Ying, J. Y., & Zhang, Y. (2022). Surface Antimicrobial Treatment by Biocompatible, Vertically Aligned Layered Double Hydroxide Array. Advanced Materials Interfaces, 9(9), 2101872. Portico. https://doi.org/10.1002/admi.202101872

Vertically aligned layered double hydroxide (V-LDH) array has been growing on various substrates by a simple solution hydrolysis method. The surface shows good topology with LDH edges extending upward, which can potentially rupture the attached bacteria cells and kill them. V-LDH after calcination shows remarkable enhanced antibacterial properties. Not only do the edges become thinner and sharper, the surface also becomes highly hydrophilic. It is found that surface potential of V-LDH does not change its antibacterial property. However, the hydrophilicity significantly enhances antibacterial properties. In vitro and in vivo studies demonstrate that the V-LDH surface has good biocompatibility. The V-LDH antibacterial coating has potentially broad applications due to its good antibacterial properties and biocompatibility.

Publisher Copyright

This research / project is supported by the National Research Foundation - NRF Competitive Research Program
Grant Reference no. : NRF-CRP19- 2017-02

This is the peer reviewed version of the following article: Yi, G., Gao, S., Lu, H., Khoo, W. Z., Liu, S., Chng, S., Yang, Y. Y., Ying, J. Y., & Zhang, Y. (2022). Surface Antimicrobial Treatment by Biocompatible, Vertically Aligned Layered Double Hydroxide Array. Advanced Materials Interfaces, 9(9), 2101872. Portico. https://doi.org/10.1002/admi.202101872 , which has been published in final form at doi.org/10.1002/admi.202101872. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions, This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.

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Institute of Bioengineering and Bioimaging