Design and synthesis of magnetic nanoparticles for biomedical diagnostics

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Design and synthesis of magnetic nanoparticles for biomedical diagnostics
Title:
Design and synthesis of magnetic nanoparticles for biomedical diagnostics
Other Titles:
Quantitative Imaging in Medicine and Surgery
Keywords:
Publication Date:
09 October 2018
Citation:
Chen Y, Ding X, Zhang Y, Natalia A, Sun X, Wang Z, Shao H. Design and synthesis of magnetic nanoparticles for biomedical diagnostics. Quant Imaging Med Surg 2018;8(9):957-970. doi: 10.21037/qims.2018.10.07
Abstract:
Abstract: Sensitive and quantitative characterization of clinically relevant biomarkers can facilitate disease diagnosis and treatment evaluation. Magnetic nanomaterials and their biosensing strategies have recently received considerable attention. Magnetic signals experience little interference from native biological background as most biological molecules have negligible magnetic susceptibilities and thus appear transparent to external magnetic fields. Because of this unique property, magnetic sensing can be applied to both in vivo deep tissue imaging as well as ex vivo point-of-care diagnostics. To exploit this mode of magnetic detection, new advancements in both magnetic material syntheses and sensing technologies have been made. This review focuses on recent developments of magnetic nanomaterials as image contrast agents and diagnostic sensors. These developments have not only enabled precise control of magnetic nanomaterial properties but also expanded the reach of magnetic detection for biomedical diagnostics.
License type:
Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
Funding Info:
This work was supported in part by funding from NUS Research Scholarship, MOE, NMRC, A*STAR IMCB Independent Fellowship and NUS Early Career Research Award.
Description:
All content of the AME journals is published with open access under the Creative Commons Attribution-NonCommercial-NoDerivs License (CC BY-NC-ND 4.0). All articles published with open access will be immediately and permanently free for everyone to read, download, copy, and distribute as defined by the applied license. Free access and usage Permitted third party reuse is defined by the CC BY-NC-ND 4.0 license. This license allows users to copy and distribute the article under the following conditions: this is not done for commercial purposes and does not permit the further distribution of the article if it is changed or edited in any way. the user gives appropriate credit (with a link to the formal publication through the relevant DOI) and provides a link to the license, but does not in an any way imply that the licensor is endorsing the user or the use of the work. no derivatives including the remixing, transforming, or building upon of the material is allowed for distribution. The full details of the license are available at https://creativecommons.org/licenses/by-nc-nd/4.0/.
ISSN:
2223-4292
2223-4306