Increased oral processing and a slower eating rate increase glycaemic, insulin and satiety responses to a mixed meal tolerance test

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Increased oral processing and a slower eating rate increase glycaemic, insulin and satiety responses to a mixed meal tolerance test
Title:
Increased oral processing and a slower eating rate increase glycaemic, insulin and satiety responses to a mixed meal tolerance test
Journal Title:
European Journal of Nutrition
Publication Date:
02 January 2021
Citation:
Goh, A. T., Choy, J. Y. M., Chua, X. H., Ponnalagu, S., Khoo, C. M., Whitton, C., … Forde, C. G. (2021). Increased oral processing and a slower eating rate increase glycaemic, insulin and satiety responses to a mixed meal tolerance test. European Journal of Nutrition, 60(5), 2719–2733. doi:10.1007/s00394-020-02466-z
Abstract:
Purpose: Variations in specific oral processing behaviours may contribute to differences in glucose, insulin and satiety responses to a standardised test meal. This study tested how natural variations in oral processing between slower and faster eaters contribute to differences in post-prandial glucose (PP glucose), insulin response (PP insulin) and post-meal satiety for a standardised test meal. Methods: Thirty-three participants with higher risk for type 2 diabetes consumed a standardised test-meal while being video recorded to derive specific oral processing behaviours. Plasma glucose, insulin and satiety measures were collected at baseline, during and post meal. Participants were split into slower and faster eaters using median split based on their eating rates and individual bolus properties were analysed at the point of swallow. Results: There were large variations in eating rate (p  0.05), slower eaters showed significantly higher PP insulin between 45 and 60 min (p 
License type:
Publisher Copyright
Funding Info:
Supported by Singapore Ministry of Health’s National Medical Research Council under its Centre Grant Programme (NMRC/CG/M009/2017_NUH/NUHS) & Singapore Biomedical Research Council Food Structure Engineering for Nutrition and Health (Sub-grant Grant no. H18/01/a0/E11, Awarded to PI: Forde, C. G.).
Description:
This is a post-peer-review, pre-copyedit version of an article published in European Journal of Nutrition. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00394-020-02466-z.
ISSN:
1436-6207
1436-6215
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