Attia, A. B. E., Bi, R., Dev, K., Du, Y., & Olivo, M. (2020). Clinical noninvasive imaging and spectroscopic tools for dermatological applications: Review of recent progress. Translational Biophotonics, 2(4). doi:10.1002/tbio.202000010
Abstract:
Dermatologists mainly entrust visual
clinical examinations in conjunction
with histopathology for an informed
skin condition diagnosis, which is
invasive and not adequate to assess
skin conditions still present in subcutaneous
skin layers. With emerging
complementary imaging and
spectroscopic technologies currently
available, the assessment of skin
conditions is more accessible than
before. This review article will cover these technologies including: photoacoustic
imaging, reflectance confocal microscopy, multiphoton microscopy,
optical coherence tomography and confocal Raman spectroscopy. The basic
concepts of these technologies and their configurations will be touched on,
together with their limitations and future directions. The review article will
discuss how these technologies are utilized for cutaneous applications, examining
studies accomplished either in vivo on humans or on ex vivo human
specimens.
License type:
Attribution 4.0 International (CC BY 4.0)
Funding Info:
This work was supported by intramural funding from Singapore Bioimaging The consortium, Biomedical Research Council of Agency for Science, Technology, and Research (A*STAR) and A*STAR under its Industry Alignment Fund Prepositioning Programme, Award H19H6a0025.