Omega-3 fats in pregnancy: could a targeted approach lead to better metabolic health for children?

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Omega-3 fats in pregnancy: could a targeted approach lead to better metabolic health for children?
Title:
Omega-3 fats in pregnancy: could a targeted approach lead to better metabolic health for children?
Other Titles:
Nutrition Reviews
Publication Date:
24 September 2020
Citation:
Vidit V Satokar, Wayne S Cutfield, David Cameron-Smith, Benjamin B Albert, Omega-3 fats in pregnancy: could a targeted approach lead to better metabolic health for children?, Nutrition Reviews, Volume 79, Issue 5, May 2021, Pages 574–584, https://doi.org/10.1093/nutrit/nuaa071
Abstract:
The prevalence of childhood obesity is increasing worldwide, and the children of women who are obese during pregnancy are at greatest risk. This risk may be mediated by exaggeration of the normal insulin resistance of pregnancy. Omega-3 (n-3) fats are insulin sensitizing. Supplementation during pregnancy may reduce metabolic risk and adiposity in the children. Though results from animal studies are encouraging, completed clinical trials have not demonstrated this benefit. However, to our knowledge, previous studies have not targeted women who are overweight or obese while pregnant—the group at greatest risk for insulin resistance and most likely to benefit from n-3. In this narrative review, the importance of performing clinical trials restricted to women who are overweight or obese is discussed, as is the potential importance of n-3 dose, oil source and quality, and the timing of the intervention.
License type:
Publisher Copyright
Funding Info:
BBA has received support from the Maurice Paykel Postdoctoral Fellowship and the Rutherford Fellowship.
Description:
This is a pre-copyedited, author-produced version of an article accepted for publication in Nutrition Reviews following peer review. The version of record Vidit V Satokar, Wayne S Cutfield, David Cameron-Smith, Benjamin B Albert, Omega-3 fats in pregnancy: could a targeted approach lead to better metabolic health for children?, Nutrition Reviews, Volume 79, Issue 5, May 2021, Pages 574–584, https://doi.org/10.1093/nutrit/nuaa071 is available online at: https://doi.org/10.1093/nutrit/nuaa071.
ISSN:
0029-6643
1753-4887
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