Eating behaviors moderate the associations between risk factors in the first 1000 days and adiposity outcomes at 6 years of age

Eating behaviors moderate the associations between risk factors in the first 1000 days and adiposity outcomes at 6 years of age
Title:
Eating behaviors moderate the associations between risk factors in the first 1000 days and adiposity outcomes at 6 years of age
Other Titles:
The American Journal of Clinical Nutrition
Keywords:
Publication Date:
27 March 2020
Citation:
Fogel, A., McCrickerd, K., Aris, I.M., GohA.T., Chong, Y.S., Tan, K.H., Yap, F., Shek, L.P., Meaney, M.J., Broekman, B.F.P., Godfrey, K.M., Chong, M.F.F., Cai, S., Pang, W.W., Yuan, W.L., Lee, Y.S., & Forde, C.G. (2020). Eating behaviours moderate the associations between risk factors in the first 1000 days and adiposity outcomes at age 6 years of age. American Journal of Clinical Nutrition, 111(5), pp. 997-1006. doi:10.1093/ajcn/nqaa052.
Abstract:
Background: Several risk factors in the first 1000 d are linked with increased obesity risk in later childhood. The role of potentially modifiable eating behaviors in this association is unclear. Objectives: This study examined whether the association between cumulated risk factors in the first 1000 d and adiposity at 6 y is moderated by eating behaviors. Methods: Participants were 302 children from the GUSTO (Growing Up in Singapore Towards healthy Outcomes) cohort. Risk factors included maternal prepregnancy and paternal overweight, excessive gestational weight gain, raised fasting plasma glucose during pregnancy, short breastfeeding duration, and early introduction of solid foods. Composite risk scores reflecting the prevalence and the importance of the risk factors present were computed. Adiposity outcomes were child BMI and sum of skinfolds (SSF), and candidate eating behavior moderators were portion size, eating rate, and energy intake during lunch and in an eating in the absence of hunger task. Results: Higher composite risk score predicted higher BMI z scores (B = 0.08; 95% CI: 0.04, 0.13) and larger SSF (0.70 mm; 0.23, 1.18 mm), and was associated with larger self-served food portions (5.03 kcal; 0.47, 9.60 kcal), faster eating rates (0.40 g/min; 0.21, 0.59 g/min), and larger lunch intakes (7.05 kcal; 3.37, 10.74 kcal). Importantly, the association between composite risk score and adiposity was moderated by eating behaviors. The composite risk score was unrelated to SSF in children who selected smaller food portions, ate slower, and consumed less energy, but was positively associated with SSF among children who selected larger food portions, ate faster, and consumed more energy (eating behavior × risk score interactions: P < 0.05). Conclusions: The association between risk factors in the first 1000 d and adiposity at 6 y varies by eating behaviors, highlighting modifiable behavioral targets for interventions.
License type:
PublisherCopyrights
Funding Info:
This research is supported by the Singapore National Research Foundation under its Translational and Clinical Research (TCR) Flagship Programme and administered by the Singapore Ministry of Health's National Medical Research Council, Singapore- NMRC/TCR/004-NUS/2008; NMRC/TCR/012-NUHS/2014. Additional funding is supported by the Singapore Institute for Clinical Sciences, A*STAR and Nestec: Nestec–Epigen fund: ‘Child Eating Behavior & Obesity’ (G0067; BMSI/15-300-SICS). KMG is supported by UK Medical Research Council grant MC_UU_12011/4, the National Institute for Health Research (NIHR) (asan NIHR Senior Investigator via grant NF-SI-0515-10042 and through the NIHR Southampton Biomedical Research Centre), and the European Union’s Erasmus+ Capacity-Building ENeASEA Project and Seventh Framework Programme (FP7/2007-2013), project Early Nutrition, under grant agreement no. 289346.
Description:
This is a pre-copyedited, author-produced version of an article accepted for publication in The American Journal of Clinical Nutrition following peer review. The version of record Anna Fogel, Keri McCrickerd, Izzuddin M Aris, Ai Ting Goh, Yap-Seng Chong, Kok Hian Tan, Fabian Yap, Lynette P Shek, Michael J Meaney, Birit F P Broekman, Keith M Godfrey, Mary F F Chong, Shirong Cai, Wei Wei Pang, Wen Lun Yuan, Yung Seng Lee, Ciarán G Forde, Eating behaviors moderate the associations between risk factors in the first 1000 days and adiposity outcomes at 6 years of age, The American Journal of Clinical Nutrition, Volume 111, Issue 5, May 2020, Pages 997–1006, https://doi.org/10.1093/ajcn/nqaa052 is available online at: https://doi.org/10.1093/ajcn/nqaa052.
ISSN:
1938-3207
0002-9165
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