Hong, W. SNXs take center stage in endosomal sorting. Nat Cell Biol 21, 1175–1177 (2019). https://doi.org/10.1038/s41556-019-0401-7
Endosomes are central stations for converging proteins from biosynthetic pathways and endocytic routes. Many endosomal proteins are sorted to the plasma membrane or Golgi despite the lysosome being the primary endosomal fate. SNX5/6 are now revealed to decode a conserved bipartite signal to mediate protein sorting to the Golgi or plasma membrane.