L.S.W.L. is supported by an A*STAR Graduate Scholarship. A.K.K.T. is supported by the Institute of Molecular and Cell Biology (IMCB), A*STAR, A*STAR JCO Career Development Award (CDA) 15302FG148, NMRC/OFYIRG/018/2016-00, A*STAR ETPL Gap Funding ETPL/18-GAP005-R20H, Lee Foundation Grant SHTX/LFG/002/2018, Skin Innovation Grant SIG18011, NMRC OF-LCG/DYNAMO, FY2019 SingHealth Duke-NUS Surgery Academic Clinical Programme Research Support Programme Grant, Precision Medicine
and Personalised Therapeutics Joint Research Grant 2019, SingHealth Duke-NUS Transplant Centre - Multi-Visceral Transplant Fund Award and the Industry Alignment Fund - Industry Collaboration Project
(IAF-ICP). This work was also supported by a National Institutes of Health Grant R01 DK67536, the Harvard Stem Cell Institute (R.N.K.), NIH/NIDDK grant K01 DK098285 (J.A.P.), Harvard Stem Cell Institute (HSCI) and a U.S. National Institutes of Health (NIH) F31DK098931 (I.A.V), Western Norway Regional Health Authority,
Diabetesforbundet, Bergen Research Foundation, and the Novo Nordisk Foundation (H.R.), Norsk Endokrinologisk forenings reisestipend, Diabetesforbundet and Inger R. Haldorsens legat (H.V.).