H. Fu et al., "Automatic anterior chamber angle structure segmentation in AS-OCT image based on label transfer," 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Orlando, FL, 2016, pp. 1288-1291. doi: 10.1109/EMBC.2016.7590942
Abstract:
The anterior chamber angle (ACA) plays an important role for diagnosis and treatment of angle-closure glaucoma. Anterior Segment Optical Coherence Tomography (AS-OCT) imaging is qualitative and quantitative assessment for the ACA structure. In this paper, we propose a novel fully automatic segmentation method for anterior chamber angle structure in AS-OCT. In our method, the initial labels are obtained by using label transfer from the AS-OCT reference dataset. Then, these labels are refined and utilized as the landmarks to support the structure segmentation. Finally, the major clinical structures: corneal boundary, iris region, and trabecular-iris contact, are extracted as the segmentation result. Experiments show that our proposed method achieve the satisfactory segmentation performance on the clinical AS-OCT dataset. Our proposed method has potential in the applications of clinical ACA parameter measurement and automatic glaucoma classification.
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