Palladium-catalyzed decarboxylative cross-coupling of 3-pyridyl and 4-pyridyl carboxylates with aryl bromides

Palladium-catalyzed decarboxylative cross-coupling of 3-pyridyl and 4-pyridyl carboxylates with aryl bromides
Title:
Palladium-catalyzed decarboxylative cross-coupling of 3-pyridyl and 4-pyridyl carboxylates with aryl bromides
Other Titles:
Tetrahedron Letters
Keywords:
Publication Date:
02 February 2015
Citation:
Chennamaneni, L. R.; William, A. D.; Johannes, C. W., Palladium-catalyzed decarboxylative cross-coupling of 3-pyridyl and 4-pyridyl carboxylates with aryl bromides. Tetrahedron Letters 2015, 56 (11), 1293-1296.
Abstract:
Decarboxylative cross-coupling of 3-pyridyl and 4-pyridyl carboxylates with aryl bromides is reported. Using a bimetallic system of Cu2O and Pd(PPh3)4, the scope of the reaction is demonstrated by the synthesis of 27 pyridine-containing biaryls in moderate to good yields.
License type:
http://creativecommons.org/licenses/by-nc-nd/4.0/
Funding Info:
Financial support provided by Institute of Chemical and Engineering Sciences, A*STAR (ICES/12-242A02).
Description:
ISSN:
0040-4039
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