We propose a new approach to spatiotemporally multiplex sub-holograms and stream hologram data in parallel by using multiple spatial light modulators (SLMs) to increase the spatiotemporal resolution of holographic display system. With the proposed approach, we have achieved a spatiotemporal resolution of 4.5 × 1010 pixel/s, as compared with 1.89 × 109 pixel/s of a single SLM. Each frame of computer-generated hologram video has a pixel count of 378 Mpixels and is divided into 288 sub-holograms, each of 1.31 Mpixels. During the playback of holographic video, these sub-holograms are spatiotemporally multiplexed and streamed in parallel to form the integrated hologram within 16.67 ms, which enables full-color holographic video display with a 10-in. diagonal at a hologram data frame rate of 60 frames per second (fps). New SLM devices with higher spatiotemporal resolution need to be developed in order to meet the data bandwidth requirement of about 1012–1014 pixel/s for future 3D holographic displays