CD11b+ DCs rediscovered: implications for vaccination

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CD11b+ DCs rediscovered: implications for vaccination
Title:
CD11b+ DCs rediscovered: implications for vaccination
Other Titles:
Expert Review of Vaccines
Keywords:
Publication Date:
21 April 2014
Citation:
CD11b+ DCs rediscovered: implications for vaccination. Florent Ginhoux, Andreas Schlitzer Expert Review of Vaccines 2014 13:4, 445-447.
Abstract:
Dendritic cells (DCs) are potent antigen sensing and presenting cells, able to both initiate and orchestrate complex immune responses. DCs are optimally equipped to recognize pathogens, as well as self-antigens and vaccine components, and instruct the type, magnitude and specificity of the ensuing immunity. However, the DC population is remarkably heterogeneous and consists of multiple subsets with different ontogeny, differentiation and functional specializations. Therefore, a deeper understanding of DC subset biology is fundamental for the development and implementation of innovative vaccination strategies.
License type:
PublisherCopyrights
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Description:
ISSN:
1476-0584
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